- "In biology, epigenetics is the study of stable changes in cell function (known as marks) that do not involve alterations in the DNA sequence."
The study of changes in gene expression that do not involve changes to the underlying DNA sequence but are instead influenced by external or environmental factors, such as diet and stress.
- "The Greek prefix epi- (ἐπι- 'over, outside of, around') in epigenetics implies features that are 'on top of' or 'in addition to' the traditional genetic basis for inheritance."
- "Epigenetics most often involves changes that affect the regulation of gene expression, and that persist through cellular division."
- "Such effects on cellular and physiological phenotypic traits may result from external or environmental factors, or be part of normal development."
- "Examples of mechanisms that produce such changes are DNA methylation and histone modification."
- "Each of which alters how genes are expressed without altering the underlying DNA sequence."
- "Non-coding RNA sequences have shown to play a key role in the regulation of gene expression."
- "Gene expression can be controlled through the action of repressor proteins that attach to silencer regions of the DNA."
- "These epigenetic changes may last through cell divisions for the duration of the cell's life."
- "They may also last for multiple generations, even though they do not involve changes in the underlying DNA sequence of the organism."
- "One example of an epigenetic change in eukaryotic biology is the process of cellular differentiation."
- "During morphogenesis, totipotent stem cells become the various pluripotent cell lines of the embryo."
- "By activating some genes while inhibiting the expression of others."
- "Muscle cells, neurons, epithelium, endothelium of blood vessels, etc."
- "It can also lead to diseases such as cancer."
- "Such effects on cellular and physiological phenotypic traits may result from... or be part of normal development."
- "Epigenetics is the study of stable changes in cell function... that do not involve alterations in the DNA sequence."
- "Gene expression can be controlled through the action of repressor proteins that attach to silencer regions of the DNA."
- "Epigenetics most often involves changes that affect the regulation of gene expression, and that persist through cellular division."
- "One example of an epigenetic change in eukaryotic biology is the process of cellular differentiation."