Pharmaceutical formulation chemistry

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Introduction to pharmaceutical dosage forms and their properties, principles of formulation design, drug delivery systems.

Introduction to Medicinal Chemistry: Covers the historical perspective of medicinal chemistry, the Drug discovery and development process, and the role of medicinal chemists in drug development, including the various stages of drug design.
Biochemistry: This will involve the biochemical pathways that are targeted by drugs, including DNA replication, protein synthesis, and enzymatic activities. It covers topics such as amino acids, carbohydrates, lipids, nucleotides and proteins.
Organic Chemistry: Including structure and properties of organic molecules, their reactivity and inter-conversion, and the mechanisms of organic reactions.
Pharmacology: The study of how drugs interact with living organisms to produce a therapeutic effect. This involves exploring the mechanisms of how drugs work at the molecular, cellular, and organism level.
Analytical Chemistry: The analytical techniques used in the formulation and analysis of medicinal compounds. This includes analytical methods such as chromatography, spectroscopy and spectrometry.
Pharmacokinetics: The study of how drugs are absorbed, distributed, metabolized, and excreted in the body. It covers topics like absorption, distribution, metabolism and excretion of drugs.
Biopharmaceuticals: This involves the study and development of biologic drugs, which are derived from living organisms. It covers topics like genetic engineering, protein structure and production, and drug delivery methods.
Physical Chemistry: Includes the principles of kinetics, thermodynamics, and other physical properties of drugs, such as solubility, dissolution, and partitioning.
Formulation Science: Development of formulations of drugs and their delivery systems. Covers topics like pre-formulation studies, drug-excipient compatibility studies and their selection, processing, and packaging.
Toxicology: The study of the harmful effects of drugs on the human body. This includes exploring how drugs interact with the body that can lead to adverse reactions or side effects.
Regulatory: This involves understanding the regulatory process involved in getting a drug to market, including rules and guidelines for safety, efficacy and quality.
Quality Control: The quality control procedures for drug manufacturing, including batch record review, assays, stability testing methods, and overall quality assurance measures.
Tablets: Solid dosage forms containing active drugs, binders, disintegrants and fillers.
Capsules: Solid dosage forms containing active drugs enclosed in a gelatin shell.
Oral liquids: Liquid dosage forms which include suspensions, solutions, and syrups.
Parenteral formulations: Sterile dosage forms administered via injection or infusion.
Topical formulations: Dosage forms applied to the skin, including creams, gels, ointments, transdermal patches, and lotions.
Suppositories: Solid dosage forms intended for rectal, vaginal, or urethral administration.
Inhalation formulations: Aerosols, powders, and nebulizers for the delivery of drugs to the lungs.
Transdermal formulations: Patches or films placed on the skin for the delivery of drugs directly into the bloodstream.
Liposomal formulations: Lipid-based formulations that encapsulate active drugs, increasing their solubility and bioavailability.
Microsphere formulations: Formulations that contain microscopic spheres of drug particles, which can be injected, inhaled or administered orally.
Nanoparticle formulations: Formulation where the particle size of the drug is in the nanometer range, which enhances drug solubility, bioavailability, and circulation time in the body.
Targeted drug delivery formulations: Formulations specifically designed to target specific body regions or cell types.
Pro-drugs: Chemical forms of drugs that require metabolism in the body to activate the drug, increasing solubility and enhancing therapeutic activity.
Biologics: Formulations of biological drugs such as vaccines, cell and gene therapies, monoclonal antibodies, and recombinant proteins.
Radiolabelled formulations: Formulations that contain radioactive molecules to trace the distribution of drugs in the body.
Combination formulations: Formulations that combine two or more drugs in a single dosage form.
Modified-release formulations: Formulations that release drugs gradually over an extended period of time, providing sustained therapeutic effect.
Immediate-release formulations: Formulations that release drugs immediately after administration, providing rapid therapeutic effect.
Enteric-coated formulations: Formulations that have an outer coating that resists gastric acid to prevent drug degradation and absorption in the stomach.
Fixed-dose combinations: Formulations that contain a fixed dose of two or more active drugs, also known as co-formulations.
"The process in which different chemical substances, including the active drug, are combined to produce a final medicinal product."
"To produce a final medicinal product."
"In pharmaceutics."
"In a way that includes dosage form."
"The combination of different chemical substances."
"The active drug."
"A final medicinal product."
"The process in which different chemical substances combine to produce a final medicinal product."
"The field in which pharmaceutical formulation is studied."
"The way the word formulation is often used."
"To produce a final medicinal product."
"The process in which different chemical substances are combined."
"A dosage form."
"A final medicinal product."
"The active drug and other components."
"Different chemical substances."
"The result of pharmaceutical formulation."
"To produce a final medicinal product."
"In a way that includes dosage form."
"A final medicinal product."