"Pharmacogenomics is the study of the role of the genome in drug response."
The study of the genetic basis of individual variability in drug response, with the aim of optimizing drug treatments based on an individual's genetic makeup.
"Pharmacogenomics analyzes how the genetic makeup of a patient affects their response to drugs."
"Pharmacogenomics correlates DNA mutations with pharmacokinetic, pharmacodynamic, and/or immunogenic endpoints."
"Pharmacogenomics aims to develop rational means to optimize drug therapy, with regard to the patients' genotype, to achieve maximum efficiency with minimal adverse effects."
"Pharmacogenomics deviates from the 'one-dose-fits-all' approach by optimizing drug treatments based on the patients' genotype."
"Pharmacogenomics attempts to eliminate trial-and-error in prescribing, allowing physicians to take into consideration their patient's genes and how this may affect the efficacy of treatments."
"Such approaches promise the advent of precision medicine and even personalized medicine, in which drugs and drug combinations are optimized for narrow subsets of patients or even for each individual's unique genetic makeup."
"It hopes to achieve better treatment outcomes and greater efficacy, and reduce drug toxicities and adverse drug reactions (ADRs)."
"For patients who do not respond, alternative therapies can be prescribed that would best suit their requirements."
"Two possible types of input can be used: genotyping, or exome or whole genome sequencing."
"Sequencing provides many more data points, including detection of mutations that prematurely terminate the synthesized protein (early stop codon)."
"It deals with the influence of acquired and inherited genetic variation on drug response."
"Pharmacogenomics aims to develop rational means to optimize drug therapy."
"Pharmacogenomics promises the advent of precision medicine and even personalized medicine."
"Pharmacogenomics focuses on the role of the genome in drug response."
"Pharmacogenomics correlates DNA mutations with pharmacokinetic, pharmacodynamic, and/or immunogenic endpoints."
"Pharmacogenomics aims to explain a patient's response (or lack of it) to a treatment."
"Pharmacogenomics aims to deviate from the 'one-dose-fits-all' approach."
"Pharmacogenomics attempts to reduce drug toxicities and adverse drug reactions (ADRs)."
"Pharmacogenomics allows physicians to take into consideration a patient's genes and their functionality to enhance the efficacy of their current or future treatments."