"Comparative genomics is a field of biological research in which the genomic features of different organisms are compared."
The study of the similarities and differences between the genomes of different organisms, providing insights into evolution and biological function.
"The genomic features may include the DNA sequence, genes, gene order, regulatory sequences, and other genomic structural landmarks."
"To study basic biological similarities and differences as well as evolutionary relationships between organisms."
"The major principle of comparative genomics is that common features of two organisms will often be encoded within the DNA that is evolutionarily conserved between them."
"Comparative genomic approaches start with making some form of alignment of genome sequences and looking for orthologous sequences (sequences that share a common ancestry) in the aligned genomes and checking to what extent those sequences are conserved."
"Virtually started as soon as the whole genomes of two organisms became available (that is, the genomes of the bacteria Haemophilus influenzae and Mycoplasma genitalium) in 1995."
"With the explosion in the number of genome projects due to the advancements in DNA sequencing technologies, particularly the next-generation sequencing methods in late 2000s, this field has become more sophisticated."
"Comparative genomics has revealed high levels of similarity between closely related organisms, such as humans and chimpanzees."
"It has also showed the extreme diversity of the gene composition in different evolutionary lineages."
"Based on these, genome and molecular evolution are inferred and this may in turn be put in the context of, for example, phenotypic evolution or population genetics."
"The genomic features may include the DNA sequence, genes, gene order, regulatory sequences, and other genomic structural landmarks."
"Looking for orthologous sequences (sequences that share a common ancestry) in the aligned genomes and checking to what extent those sequences are conserved."
"The advancements in DNA sequencing technologies, particularly the next-generation sequencing methods in late 2000s."
"Comparative genomics is now a standard component of the analysis of every new genome sequence."
"Genome and molecular evolution are inferred and this may in turn be put in the context of, for example, phenotypic evolution or population genetics."
"The genomic features of different organisms are compared."
"Common features of two organisms will often be encoded within the DNA that is evolutionarily conserved between them."
"Virtually started as soon as the whole genomes of two organisms became available (that is, the genomes of the bacteria Haemophilus influenzae and Mycoplasma genitalium) in 1995."
"It has also showed the extreme diversity of the gene composition in different evolutionary lineages."
"The explosion in the number of genome projects due to the advancements in DNA sequencing technologies, particularly the next-generation sequencing methods in late 2000s."