- "The function of inflammation is to eliminate the initial cause of cell injury, clear out necrotic cells and tissues damaged from the original insult and the inflammatory process, and initiate tissue repair."
Covers the process of inflammation, its causes, the cells involved, and the outcomes. Also explains the process of tissue repair and regeneration, and the factors that influence it.
Introduction to Inflammation: Overview of the process of inflammation and its role in tissue repair.
Acute Inflammation: Causes, symptoms, and mechanisms of acute inflammation and its resolution.
Chronic Inflammation: Causes, symptoms, and mechanisms of chronic inflammation and its effects on tissues.
Cells of Inflammation: Classification, function, and sources of cells involved in the process of inflammation.
Mediators of Inflammation: Classification, function, and sources of various mediators of inflammation involved in the process of inflammation.
Inflammatory Response: Detailed mechanisms of the inflammatory response, including hyperemia, exudation, and leukocyte migration.
Resolution of Inflammation: Mechanisms involved in the resolution of inflammation and repair of injured tissue.
Immune System and Inflammation: The relationship between the immune system and inflammation, including the role of cytokines and chemokines.
Wound Healing: The various stages of wound healing including inflammation, proliferation, and remodeling.
Regeneration and Remodeling: The processes of regeneration and remodeling of damaged tissues following inflammation.
Fibrosis: The development of fibrosis as a result of chronic inflammation and its effects on tissue function.
Inflammatory Diseases: A detailed discussion of various inflammatory diseases, including their causes, symptoms, and pathological mechanisms.
Diagnostic Techniques: Various diagnostic techniques used to identify inflammation and its associated diseases, including imaging and laboratory tests.
Therapeutic Options: A discussion of various therapeutic options available for managing inflammation and its associated diseases.
Nutritional and Lifestyle Factors: The impact of nutritional and lifestyle factors on inflammation and tissue repair.
Acute inflammation: This is a localized response to cellular injury, characterized by pain, redness, swelling, and heat.
Chronic inflammation: This is a long-term response to tissue damage, characterized by the presence of immune cells, fibrosis, and tissue destruction.
Granulomatous inflammation: This is a particular type of chronic inflammation characterized by the presence of granulomatous lesions, which are made up of aggregates of macrophages.
Purulent inflammation: This is a type of acute inflammation characterized by the production of pus, which is made up of dead white blood cells, bacteria, and tissue debris.
Fibrinous inflammation: This is a type of acute inflammation characterized by the deposition of fibrin in the affected tissue, resulting in the formation of a fibrinous exudate.
Ulcerative inflammation: This is a type of chronic inflammation characterized by the formation of ulcers in the affected tissue.
Angiogenic inflammation: This is a type of acute and chronic inflammation characterized by the formation of new blood vessels in the affected tissue.
Resolution and repair: The body's natural response to inflammation, characterized by the healing of damaged tissue and the return to homeostasis. The process involves the removal of cellular debris, the production of new tissue, and the remodeling of damaged tissue.
- "The five cardinal signs are heat, pain, redness, swelling, and loss of function (Latin calor, dolor, rubor, tumor, and functio laesa)."
- "Inflammation can be classified as either acute or chronic."
- "Acute inflammation is the initial response of the body to harmful stimuli, and is achieved by the increased movement of plasma and leukocytes (in particular granulocytes) from the blood into the injured tissues."
- "Prolonged inflammation, known as chronic inflammation, leads to a progressive shift in the type of cells present at the site of inflammation, such as mononuclear cells, and is characterized by simultaneous destruction and healing of the tissue from the inflammatory process."
- "Inflammation has also been classified as Type 1 and Type 2 based on the type of cytokines and helper T cells (Th1 and Th2) involved."
- "Inflammation is not a synonym for infection."
- "Infection describes the interaction between the action of microbial invasion and the reaction of the body's inflammatory response—the two components are considered together when discussing an infection, and the word is used to imply a microbial invasive cause for the observed inflammatory reaction."
- "Too much inflammation, in the form of chronic inflammation, is associated with various diseases, such as hay fever, periodontal disease, atherosclerosis, and osteoarthritis."
- "Prolonged inflammation, known as chronic inflammation, leads to a progressive shift in the type of cells present at the site of inflammation, such as mononuclear cells, and is characterized by simultaneous destruction and healing of the tissue from the inflammatory process."
- "Inflammation is a generic response, and therefore it is considered as a mechanism of innate immunity, as compared to adaptive immunity, which is specific for each pathogen."
- "Too little inflammation could lead to progressive tissue destruction by the harmful stimulus (e.g. bacteria) and compromise the survival of the organism."
- "Too much inflammation, in the form of chronic inflammation, is associated with various diseases, such as hay fever, periodontal disease, atherosclerosis, and osteoarthritis."
- "The function of inflammation is to eliminate the initial cause of cell injury, clear out necrotic cells and tissues damaged from the original insult and the inflammatory process, and initiate tissue repair."
- "The inflammatory response involves immune cells, blood vessels, and molecular mediators."
- "Inflammation, on the other hand, describes purely the body's immunovascular response—whatever the cause may be. But because of how often the two are correlated, words ending in the suffix -itis (which refers to inflammation) are sometimes informally described as referring to infection."
- "Inflammation is a generic response, and therefore it is considered as a mechanism of innate immunity, as compared to adaptive immunity, which is specific for each pathogen."
- "Prolonged inflammation, known as chronic inflammation, leads to a progressive shift in the type of cells present at the site of inflammation, such as mononuclear cells, and is characterized by simultaneous destruction and healing of the tissue from the inflammatory process."
- "Acute inflammation is the initial response of the body to harmful stimuli, and is achieved by the increased movement of plasma and leukocytes (in particular granulocytes) from the blood into the injured tissues."
- "Too much inflammation, in the form of chronic inflammation, is associated with various diseases, such as hay fever, periodontal disease, atherosclerosis, and osteoarthritis."